Season one of the show premiered on April 19, 2009, and season two premiered on October 26, 2009.
The members of the cast appear as themselves.
- Bartolo "Buddy" Valastro The only son of Buddy Sr. and Mary.
- Mary Valastro Bought the bakery with her husband in 1964.
- Lisa Valastro Buddy's wife.
- Grace Faugno The eldest child of Buddy Sr. and Mary.
- Joe Faugno Grace's husband.
- Maddalena "Madeline" Castano The second eldest daughter of Buddy Sr. and Mary.
- Mauro Castano Madeline's husband and Buddy's right hand man.
- Mary Sciarrone The middle child of Buddy Sr. and Mary.
- Lisa Gonzalez The youngest daughter of Buddy Sr. and Mary. In "Aquarium Adventures and an Announcement", it is announced that she is pregnant.
- Remy Gonzalez Lisa's husband.
- Frank Amato, Jr. Buddy's first cousin and the godfather of his son, Marco.
- Danny Dragone An employee and close family friend.
- Sal Picinich Started working at the bakery in 1964 and is one of Buddy's most trusted employees.
- Stephanie "Sunshine" Fernandez Buddy's first intern and she was also the first woman to work upstairs.
- Christine Campanelli The second woman to work upstairs.
- Violet Valentin Buddy's third intern.
- Daniella Storzillo An employee and close family friend.
- Toni Walton An employee.
- Kevin "Stretch" Krand The delivery boy, known for dropping/creating mass destruction to the cakes Buddy entrusts him with to deliver.
- Cousin Anthony The delivery boy, episodes 8 - present
- Tony Albanese Buddy's second intern, Season 1